Description: Activated B6, Pyridoxal-5-phosphate (P5P), 20mg, 60 capsules
Biological Activity: P5P is the activated form of vitamin B6 (pyridoxine) and plays a fundamental role in amino acid metabolism, heme biosynthesis, neurotransmitter biosynthesis, collagen formation and glucocorticoid action. Alone and together with other enzymes, P5P facilitates the release of stored energy from the liver and muscles and facilitates the production of antibodies and red blood cells.
True deficiencies of B6 are very rare in most countries, although some groups, often as a result of illness, will have marginal levels of B6 that require supplementation. These groups will also often have deficiencies in other Vitamin B groups such as Vitamin B12 and folic acid. People who have anaemia, poor renal function or autoimmune disorders such as rheumatoid arthritis are at risk of B6 deficiency, as are patients who have celiac disease, ulcerative colitis, Crohn’s disease and other malabsorptive autoimmune disorders. There has been some discussion that B6 supplements can help reduce the risk of CVD, stroke and some types of cancer.
Dosage: The recommended daily dose of P5P varies between 2.5 mg and 50 mg, based on the specific deficiency or medical condition of concern.
