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From the Team at Newton's Pharmacy
Warning: Herbal extracts may interact with other therapeutic substances, or be contraindicated in certain conditions, and as a general rule are not recommended for use by children, in pregnancy and lactation, or if you are on certain prescription medications.If wondering if any of our herbal products may be of benefit to you, please complete and submit this form and get in touch by phone or email.
Disclaimer: The statements provided on this website are based on the recorded traditional use of herbs in general and should not be viewed as therapeutic claims for the herbal teas, extracts, and blends on offer. We provide this information for educational purposes to our customers and fans of herbal and natural medicine because we believe it is important to stay connected to our roots and maintain and spread the human knowledge accumulated over centuries of traditional healing. Our herbal blends are custom-made in accordance with your needs and have not been tested for efficacy or listed on the register of therapeutic goods.
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Information and statements regarding dietary supplements have not been evaluated by the Therapeutic Goods Administration (TGA) and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
May relieve stress and anxiety
A study in 40 women ages 20–50 found that taking 250 mg of magnolia and phellodendron bark extract 3 times a day resulted in greater relief of short-term and temporary anxiety than taking a placebo (1)
A second study of the same magnolia and phellodendron bark extract in 56 adults observed that consuming 500 mg of the extract per day resulted in significantly lower cortisol levels and improved mood (2). Lastly, a study in rodents noted that a mixture of honokiol and magnolol caused antidepressant-like effects, including improvements in serotonin levels in the brain and reductions in corticosterone levels in the blood (3).
May improve sleep
A study in mice found a magnolol dose of 2.3–0.9 mg per pound (5–25 mg per kg) of body weight significantly decreased sleep latency, or the amount of time it takes to fall asleep (4). The same study observed that the same dose increased REM (rapid eye movement) and non-REM sleep.
Magnolia bark’s effects on sleep appear to be closely connected to the activity of the GABA(A) receptors in the central nervous system. This makes sense, as it’s known that GABA(A) receptor activity is closely associated with sleep (5).
May improve symptoms of menopause
A 24-week study in 89 menopausal women experiencing symptoms of sleep and mood alterations were given a supplement containing 60 mg of magnolia bark extract and 50 mg of magnesium daily. The women experienced significant improvements in insomnia, anxiety, mood, and irritability (6). A similar study in more than 600 menopausal women found that consuming a magnolia bark supplement daily for 12 weeks relieved symptoms of insomnia, irritability, and anxiety (7).
May protect against the effects of oxidative stress and inflammation
Research on honokiol has found that it can reduce inflammation in the brain and spinal cord specifically, partly due to its ability to cross the blood-brain barrier (8). Based on research in mice, some scientists believe that honokiol may help combat aging by increasing antioxidant enzymes and decreasing levels of methane dicarboxylic aldehyde. (9)
References:
1. https://www.ncbi.nlm.nih.gov/pubmed/18426577
2. https://www.ncbi.nlm.nih.gov/pubmed/23924268
3. https://www.ncbi.nlm.nih.gov/pubmed/18093712
4. https://www.ncbi.nlm.nih.gov/pubmed/22771461
5. https://www.ncbi.nlm.nih.gov/pubmed/22445602
6. https://www.ncbi.nlm.nih.gov/pubmed/16957676
7. https://www.ncbi.nlm.nih.gov/pubmed/21311416
8. https://www.ncbi.nlm.nih.gov/pubmed/28817221
9. https://www.ncbi.nlm.nih.gov/pubmed/27659301
