1. Antimicrobial Herbs
These herbs have natural antibacterial, antiviral, or antifungal properties and may help suppress Borrelia and co-infections like Babesia, Bartonella, and Ehrlichia.
• Japanese Knotweed (Polygonum cuspidatum)
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Contains resveratrol and other polyphenols that inhibit inflammation and cross the blood-brain barrier, making it useful for neurological Lyme symptoms.
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Modulates immune response and suppresses Borrelia activity.
• Cat’s Claw (Uncaria tomentosa)
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Immune-stimulating and anti-inflammatory.
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May help reduce joint pain and neurological symptoms associated with Lyme.
• Andrographis (Andrographis paniculata)
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Broad-spectrum antimicrobial.
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Supports immune function and may help clear bacterial infections.
• Cryptolepis (Cryptolepis sanguinolenta)
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Used traditionally in Africa for malaria and bacterial infections.
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Has potent antibacterial properties shown effective against Borrelia in vitro.
• Sarsaparilla (Smilax spp.)
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Binds endotoxins and may reduce die-off reactions (Herxheimer response).
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Useful for skin, muscle, and joint involvement.
• Sweet Wormwood (Artemisia annua)
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Traditionally used against parasites and co-infections like Babesia.
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Often used in combination protocols for its antimalarial and antimicrobial effects.
2. Immune-Modulating Herbs
These herbs do not directly kill bacteria but help the body recognize and clear infections.
• Astragalus (Astragalus membranaceus)
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Supports immune system resilience in early-stage or preventive Lyme support.
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Not typically used in chronic Lyme as it may overstimulate autoimmunity in late-stage cases.
• Reishi and Cordyceps Mushrooms
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Help balance immune response and reduce inflammation.
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Support adrenal function and energy.
• Echinacea
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Traditionally used to activate immune defenses during acute infections.
3. Detoxification and Liver Support
Lyme treatment often produces toxins from bacterial die-off, which can worsen symptoms. Detoxification support helps the body eliminate these more efficiently.
• Milk Thistle (Silybum marianum)
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Protects and regenerates liver cells.
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Enhances detoxification of bacterial endotoxins and drug residues.
• Dandelion Root & Burdock Root
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Gentle liver and kidney tonics.
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Promote bile flow and waste elimination.
• Chlorella & Spirulina
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Algae rich in chlorophyll that bind toxins in the gut.
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Help reduce oxidative stress and improve energy.
• Glutathione (oral or liposomal)
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A master antioxidant that supports liver detox and reduces neurological inflammation.
4. Anti-Inflammatory and Nervous System Support
Inflammation, nerve pain, and fatigue are common in chronic Lyme. These remedies calm systemic inflammation and support nerve health.
• Turmeric/Curcumin
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Reduces joint inflammation and neuroinflammation.
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Often combined with black pepper or liposomal delivery for better absorption.
• Omega-3 Fatty Acids (Fish Oil, Flaxseed)
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Reduce inflammatory cytokines.
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Support brain and nerve function.
• Skullcap, Lemon Balm, and Passionflower
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Calm the nervous system, reduce anxiety, and help with sleep disruption.
5. Homeopathy
Individualized remedies may be used to modulate symptoms and support the terrain of the body:
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Ledum palustre – For early tick bites and puncture wounds.
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Borrelia nosode – Used by some practitioners to stimulate an immune response against the infection.
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Gelsemium or Rhus tox – For muscular pain, fatigue, and joint stiffness.
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Hypericum – for nerve pain or injury
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Kalmia – for radiating pain and heart palpitations
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Merc sol, Arsenicum, Apis, Bryonia – depending on specific symptom patterns
6. Lifestyle & Nutritional Support
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Anti-inflammatory Diet: Whole foods, low sugar, high in leafy greens, berries, lean proteins, and healthy fats.
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Hydration: Helps flush toxins.
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Sleep & Rest: Crucial for immune restoration.
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Gentle Movement: Yoga or walking may reduce stiffness and improve lymphatic flow.
Integrative Approaches at Newtons Pharmacy
At Newtons Compounding Pharmacy, we support natural and integrative strategies for Lyme disease, including:
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Custom Herbal Extract Blends: Japanese Knotweed, Cat’s Claw, Andrographis, Cryptolepis
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Liver & Lymphatic Detox Blends: Including milk thistle, burdock, and dandelion
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Compounded Liposomal Glutathione or Curcumin for inflammation
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Immune Formulations with astragalus, mushrooms, and vitamins
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Neurological Calm Support: Herbal nerve tonics and sleep aids
Note: Natural remedies can be highly supportive for Lyme recovery, but should be used under guidance, especially when combined with conventional treatments or in cases of neurological involvement, co-infections, or Herxheimer reactions.
Contact Newtons Pharmacy for personalized herbal protocols, detox support, or practitioner collaboration.