In healthy people, policosanol in Metagenics Cholesstanol has been shown to or may:
- Improve the LDL:HDL ratio.
- Assist the maintenance of healthy cholesterol levels.
- Easy once a day prescribing for improved compliance.
Ingredients: Metagenics Cholesstanol
|Each tablet contains:
|Sugar cane wax alcohol
Metagenics Cholesstanol is free from animal products, corn, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast, soy protein, starches and salt. Metagenics Cholesstanol is free from artificial colours, flavours and preservatives.
Clinical Benefits: Metagenics Cholesstanol
A literature review of policosanol and cholesterol studies, have shown 10 mg of policosanol to effectively assist the maintenance of healthy cholesterol levels and improve the LDL:HDL ratio in healthy individuals. These studies have reported significant differences in total cholesterol by 17% and in low density lipoprotein (LDL) cholesterol by 21%. There were also significant differences in high density lipoprotein (HDL) cholesterol by 8% (Figure One).1
Naturally derived, policosanol: Metagenics Cholesstanol contains policosanols that are naturally derived sugar cane wax alcohols. Policosanol has been shown to assist the maintenance of healthy cholesterol levels and improve the LDL:HDL ratio in healthy volunteers in several clinical trials.1,2,3 The mechanism of action for the reduction in cholesterol synthesis is via interference with the catalytic activity of HMG CoA reductase.4 A study has also demonstrated policosanol to decrease the susceptibility of LDL-C to lipid peroxidation in vitro.2
Figure One: Policosanol and LDL:HDL Ratio.
Gouni-Berthold I & Berthold HK. Policosanol: Clinical pharmacology and therapeutic significance of a new lipid-lowering agent. American Heart Journal 2002; 143(2); 356-365.