Hair loss or Baldness involves the loss of hair on the head. The most common form of baldness is a progressive hair thinning condition called androgenetic alopecia, commonly referred to as male pattern baldness (MPB) or female pattern baldness (FPB).
For many years, scientists thought that MPB was caused by the predominance of the male sex hormone, testosterone. While testosterone is at the core of the balding process, it is now known that Dihydrotestosterone (DHT) a metabolite of testosterone, is the primary agent responsible for premature hair loss.
Human hair, like nails, is composed of the fibrous protein keratin—the only non-living tissue of the body. Hair grows continuously from follicles in the scalp, nourished by nutrient-rich blood. While it is normal to lose 50–100 hairs per day, excess loss without sufficient regrowth can lead to thinning or baldness.
Causes of Hair Loss
Hair loss may result from stress, nutritional deficiencies, hormonal shifts, thyroid imbalance, immune disorders, environmental factors, or genetics. It may also be triggered by infections or medical treatments such as chemotherapy.
Testosterone converts to DHT via the enzyme Type II 5-alpha reductase which is held in a hair follicle’s oil glands. The level of DHT binding to the receptors in the scalp hair follicles is of major concern in terms of the underlying cause of hair loss. DHT reduces the growth phase of the hair follicle causing them to shrink. Simultaneously, the membrane in the scalp thickens, becoming inelastic and restricting blood circulation. Eventually, the follicle atrophies to a point where hair growth is no longer possible. The normal rest-grow cycle of the hair follicle is altered and follicles remain dormant for the majority of the time. As a result, hairs fall out at the same rate, but are not replaced. Eventually, all the hairs revert to the rest phase and a bald spot, or baldness results.
Other causes of hair loss include: Stress, Medications including some blood pressure, cholesterol, cancer, acne and birth control tablets; Hormone imbalances – low progesterone, low thyroid, high DHEA and testosterone; Fungal infections and Nutritional deficiencies such as Vit D and/or iron deficiencies.
Compounded Prescription Treatments for Hair Loss
Custom topical formulations offer powerful, personalized solutions by combining multiple active agents into one treatment. These products must be prescribed by a healthcare provider and are compounded by specialty pharmacies.
Combination Topical Solutions: A compounded formula can combine multiple effective agents (like Minoxidil, Finasteride, Tretinoin, and Spironolactone) in one application, simplifying the treatment regimen.
Popular Combination:
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Finasteride 1% with Minoxidil 7% Topical Foam: Designed for androgenetic alopecia (male and female pattern baldness), this high-strength combination supports regrowth and reduces hair thinning.
Available Active Ingredients:
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Minoxidil (higher concentrations than OTC versions)
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Finasteride (topical version to reduce systemic exposure)
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Tretinoin (improves scalp absorption)
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Spironolactone (especially effective for female hair loss)
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Latanoprost (prostaglandin analogue used for regrowth stimulation)
Especially for Women:
- Spironolactone - Anti-androgen particularly effective for female pattern hair loss
- Your compounded topical hair loss treatment may include one or a combination of ingredients: Finasteride, Spironolactone, Tretinoin and Minoxidil
Additional Options:
- Latanoprost Topical - Can be compounded with other ingredients and mimics prostaglandin chemicals
Advantages of Compounding
- Avoiding Allergens and Irritants - Compounding can ensure the absence of preservatives that may cause reactions
- Custom strengths not available commercially
- Multiple ingredients in one application for convenience
- Truly individualized solutions targeting different causes of hair loss
Important: Most effective compounded hair loss treatments require a prescription from a doctor, as they contain prescription-strength active ingredients that aren't available over-the-counter.
Natural Hair Loss Treatment: Newton’s Special Hair Lotion
Newton’s Special Hair Lotion is a popular natural remedy, formulated to strengthen hair roots and promote regrowth. The formula is based on decades of herbal tradition.
Main Ingredients:
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Organic Castor Oil
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Rosemary Essential Oil
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Arnica Tincture
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Cayenne Tincture
Directions: Apply to the scalp in the evening, massage gently, and rinse after 15 minutes.
Supplemental Nutrients & Herbal Remedies
Nutritional and herbal support can significantly improve hair strength, thickness, and scalp health. These supplements nourish follicles and address underlying causes of hair thinning.
Essential Oils and Herbal Supplements:
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Evening Primrose Oil: Rich in gamma-linolenic acid (GLA); promotes scalp health and reduces flaking.
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Flaxseed Oil: Supplies omega-3s for scalp hydration and hair shine; also helps manage dandruff and eczema.
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Black Seed Oil: Traditionally used to support regrowth and reduce inflammation.
Vitamins and Minerals:
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Vitamin B-Complex: Supports overall hair and skin health. Look for biotin, B6, B12, folic acid, and PABA.
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Biotin (1,000 mcg/day): Strengthens hair shafts and supports new growth in deficiency-related loss.
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Zinc (30 mg/day): Prevents hair thinning, especially when thyroid function is suboptimal.
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Copper (2 mg/day): Balances zinc use and may help restore pigment to graying hair.
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Selenium (200 mcg twice daily): Supports scalp and follicle integrity. Do not exceed 600 mcg daily.
Additional Care Strategies
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Diet & Hydration: Eat a varied diet rich in whole grains, legumes, vegetables, and healthy fats. Avoid restrictive diets that reduce key nutrients.
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Scalp Massage: Weekly massage improves circulation and relieves tension, supporting healthy follicle function.
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Protect Hair: Avoid excessive heat and chemical exposure. Use mild shampoos and natural conditioners.
Common Aromatherapy Oils Used in Hair Care:
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Allspice
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Carnation
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Parsley
Conclusion:
Hair health relies on a combination of internal balance and external support. Whether through prescription compounded formulations or time-tested natural remedies like Newton’s Hair Lotion and flaxseed oil, consistent use and targeted care offer the best chance for noticeable improvement. Always consult with a practitioner for tailored treatment options.